Newsy
Multiplex Biomedica
Biomedica is your go to partner for modern and best in class multiplex solutions and workflows that fit the needs of every research institution and clinical laboratory.
It is often more beneficial to study multiple targets and analytes, as opposed to just one, for several reasons:
- This approach provides a more comprehensive understanding: By studying multiple targets, researchers can gain a more comprehensive understanding of a biological system or process. This can help to identify correlations and relationships between different targets, leading to a deeper understanding of the underlying biology.
- Increasing the statistical power: By studying more targets and analytes, researchers can increase the statistical power of their experiments. This is because larger sample sizes typically lead to more robust and reliable results, making it easier to detect differences or changes in biological systems.
- Detecting multiple biological pathways: Studying multiple targets allows researchers to identify and examine multiple biological pathways or mechanisms that may be involved in a particular biological system or process. This means you can get a more complete picture of the underlying biology.
- Enhanced reproducibility: When researchers study multiple targets and analytes, it can increase the likelihood that their results will be independently confirmed by other researchers. This is because multiple lines of evidence are often required to establish a scientific finding and studying multiple targets can provide additional lines of evidence that increase the confidence in a result.
Our strength is our flexibility in finding a solution: We offer a comprehensive range of products and services that enable researchers to move quickly and efficiently from concept to results.
Whether you want to look at multiple DNA, RNA targets or the gene expression/activation level, at a combination of proteins, or even at multiple targets in an individual cell,
Biomedica has you covered:
Gene Expression Multiplexing
The nCounter® Pro Analysis System and the Sprint Profiler provide a cost-effective automated solution for multiplex analysis of 800+ targets.
CosMx SMI is the first high-plex in situ analysis platform to provide spatial multiomics with formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue samples at cellular and subcellular resolution.
The GeoMx Digital Spatial Profiler (DSP) provides morphological context in spatial transcriptomics and spatial proteomics experiments from just one slide.
From discovery to translational research, the GeoMx DSP is the most flexible and robust spatial biology solution designed to conform to your ever-changing research needs.
Multiomics
A new approach that combines data sets from different -omic groups during analysis.
Multiomics has transformed traditional sequencing experiments by enabling simultaneous protein and gene analysis to an unprecedented depth. We offer a comprehensive library of products including antibodies, panels and cell hashtags for sample multiplexing to enable protein detection by sequencing. Explore the capabilities of TotalSeq™ reagents and see how they integrate seamlessly into existing and new workflows to discover what makes each cell unique.
NGS & RT-QPCR MicroRNA Services
We offer a broad range of high-quality RNA services including RNA extraction, Next generation sequencing (NGS) and RT-qPCR and the custom analysis of microRNA signatures. Check out our services.
Measure multiple proteins at the same time to accelerate biomarker discovery and target validation. Biomedica offers a wide range of solutions and instruments that will fit right into your workflow!
Sample Screening
Our Membrane Antibody Arrays offer quick and inexpensive analysis of multiple analytes in a simple assay.
Proteome Profiler
Membrane Antibody Arrays
There is an increasing need for tools that can rapidly screen cells for a large number of cell surface markers. Individual fluorochrome-conjugated antibodies or antibody cocktails are used as powerful tools in immunology, cancer and stem cell research.
Screen for molecules on your cells of interest with our (human/mouse) cell surface screening assays, resulting in single cell data for 350 antibodies across 71 profiling subsets.
Validation and Optimization
Quantify multiple analytes, collect even more data, and evaluate your next steps with any of the following methods. Flexibility at your fingertips.
Planar-based Assays
Our microtiter-based multiplex immunoassays contain multiple, regularly printed antibody sets within the confines of the wells. We offer both cytokine and complement multiplex solutions for various species as well as measurement services.
Cytokine and Complement Multiplex
Bead-based Assays
Bead-based multiplex assays are a type of multiplexing technology that allows researchers to study multiple targets in a single sample by using different color-coded beads, each of which is coated with a specific probe for a target. Such assays can be performed on either a conventional flow cytometer or a Luminex instrument.
Flow Cytometry Multiplexing Assays
Use multicolor flow cytometry to detect multiple cell surface and intracellular targets with multiple fluorescence-labeled antibodies in a single well of a microtiter plate.
LegendPlex
GeniePlex
Multicolor Flow Cytometry Guide
Luminex Multiplexing Assays
Luminex xMAP® technology-based immunoassays enable the simultaneous detection and quantification of multiple analytes. Save time, money, and sample with Luminex multiplex immunoassays.
Luminex Multiplex Guide
Luminex Multiplex Assay Services - Check out our services.
Highly Automated Platforms
With incredibly fast and accurate analysis, our fully automated platforms help ensure that your cell and gene therapy research meets your precise quality, purity and performance requirements. Instrument methods can be seamlessly transferred across labs and project phases, giving you consistent, reproducible results regardless of your throughput needs.
Automated ELISA Platform “Ella”
Automated WESTERN BLOT Platforms
Next Generation WESTERN PROTEIN Analyzer „Abby“
Complete PROTEIN ANALYSIS Solution “Jess”
Imaged cIEF, CE-SDS, and Imaged cIEF Fractionation “Maurice”
Pathway and Disease Assays
Quantify key targets with our ELISA Sampler Packs!
These are pre-packaged sets of 48-well precoated ELISA kits that allow scientists to study a specific area of research, such as a protein family, biological pathway, or disease.
FluoroSpot and ELISpot are used to quantify protein-secreting cells
In FluoroSpot, a cell suspension is added to the wells of a plate. Proteins secreted by the cells are captured by specific antibodies immediately after secretion and throughout the stimulation process. After cell removal, labeled or biotinylated detection antibodies are added, followed by fluorophore-labelled secondary reagents. The captured proteins become fluorescent spots, with each spot corresponding to a single cell.
FluoroSpot is the multiplex version of ELISpot
Readers with unparalleled accuracy and speed
CosMx SMI is the first high-plex in situ analysis platform to provide spatial multiomics with formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue samples at cellular and subcellular resolution.
The GeoMx Digital Spatial Profiler (DSP) provides morphological context in spatial transcriptomics and spatial proteomics experiments from just one slide.
From discovery to translational research, the GeoMx DSP is the most flexible and robust spatial biology solution designed to conform to your ever-changing research needs.
Advanced Cell Diagnostics - Understand vital gene expression patterns at single-cell resolution.
This type of assay generates precise gene expression data, allowing researchers to perform comprehensive spatial studies of 12 targets in FFPE samples and up to 48 targets in fresh and frozen sample types.
Direct visualization of RNA molecules in intact samples.
Our highly trained team of application and service technicians, as well as our service lab researchers, are always available to assist you.
Visit our service page for more info!
These are just a few examples of the many multiplexing technologies in our portfolio. The choice of technology will depend on the specific research question, the type of sample being studied, and the level of detail required. Should you have any questions please contact our local sales team.
*Please note that not all of the products are available in all of Biomedica's subsidiaries.
